Deadly Medicine: India’s Cough Syrup Horror
India is reeling from a heartbreaking tragedy after 17 children died from kidney failure linked to a toxic cough syrup called Coldrif, manufactured in Tamil Nadu. In response, the Indian government has declared three cough syrups—Coldrif, Respifresh TR, and ReLife—as toxic, triggering nationwide recalls and arrests. The World Health Organization (WHO) has also raised alarms over India’s drug safety protocols, warning of risks through unregulated channels
What Happened in Madhya Pradesh?
The children, all under five, reportedly consumed Coldrif syrup, which was later found to contain 48.6% diethylene glycol (DEG)—a deadly industrial solvent used in antifreeze. The permissible limit is just 0.1%, making the contamination nearly 500 times higher than allowed. Most of the victims were treated at a government hospital in Chhindwara, Madhya Pradesh.

Toxic Syrups and Their Makers
Here’s a breakdown of the three banned syrups:
Syrup Name | Manufacturer Location | DEG Level | Deaths Linked | Action Taken |
---|---|---|---|---|
Coldrif | Tamil Nadu (Sresan Pharma) | 48.6% | Yes (17 deaths) | Banned, owner arrested |
Respifresh TR | Gujarat (Rednex Pharma) | 1.342% | No | Recalled, production halted |
ReLife | Gujarat (Shape Pharma) | 0.616% | No | Recalled, production halted |
Sources: Moneycontrol NewsBytes Business Standard
Arrests and Suspensions
The owner of Sresan Pharmaceuticals, S Ranganathan, was arrested and will be transferred to Madhya Pradesh for further investigation . In a swift move, Tamil Nadu’s Health Minister suspended two senior drug inspectors, citing negligence in quality control.
WHO’s Warning and India’s Response
The WHO expressed deep concern over the regulatory gap in India’s domestic drug testing. Although officials confirmed that none of the syrups were exported, the WHO cautioned that illegal or unregulated distribution channels could still pose risks globally.
India’s Central Drugs Standard Control Organisation (CDSCO) has now ordered nationwide inspections of pharmaceutical units, especially those previously flagged for substandard products. The CDSCO also banned all medicinal production by the three companies involved.
Why Diethylene Glycol Is Dangerous
DEG is a sweet-tasting but highly toxic chemical. Even small amounts can cause kidney failure, neurological damage, and death, especially in children. Past incidents in Gambia, Uzbekistan, and Cameroon linked to Indian-made syrups have already led to over 140 child deaths worldwide, prompting stricter export testing rules in 2023
What Parents and Doctors Should Do
Health officials urge everyone to:
- Stop using Coldrif, Respifresh TR, and ReLife immediately
- Report any side effects such as vomiting, stomach pain, or reduced urination
- Seek urgent medical help if symptoms appear after consuming any cough syrup
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For more updates, visit WHO’s official statement and India’s CDSCO portal.
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